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Antibodies

Monoclonal Antibody to CD35 / CR1 (Follicular Dendritic Cell Marker)(Clone : SPM554)

Product Sizes
100 µg
£716.00
36-1068-100UG
About this Product
SKU:
36-1068
Additional Names:
CR1||C3BR
translate.label.attr.clone:
SPM554
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of 210-220kDa; which is identified as the complement receptor 1 (CR1)/CD35. This MAb is specific for a site in CR1 that is distal from the C3b-binding site; so that it is unable to block CR1 activity. This MAb is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b; the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Format:
Purified
Host:
Mouse
Immunogen:
Intact human monocytes
Isotype:
Mouse IgG1; kappa
Purification:
Affinity Chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg