Monoclonal Antibody to Topoisomerase (DNA) I; Mitochondrial (TOP1MT)(Clone : TOP1MT/488)
Product Sizes
100 µg
£716.00
36-1059-100UG
About this Product
- SKU:
- 36-1059
- Additional Names:
- TOP1MT
- translate.label.attr.clone:
- TOP1MT/488
- Clonality:
- Monoclonal
- Extra Details:
- DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication; recombination; and transcription; DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I; mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase; mitochondrial Topo I requires a divalent metal; either; calcium or magnesium; as well as an alkaline pH for optimal activity.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human TOP1MT protein
- Isotype:
- Mouse IgG2b; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
