Monoclonal Antibody to HCG-beta (Pregnancy & Choriocarcinoma Marker)(Clone : HCGb/459)

Product Sizes

100 µg

£716.00

36-1039-100UG

About this Product

SKU:: 36-1039
Additional Names:: CGB||CGB3
translate.label.attr.clone:: HCGb/459
Clonality:: Monoclonal
Extra Details:: This MAb reacts with a protein of 22kDa; identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein; which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical; non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH); follicle stimulating hormone (FSH); and luteinizing hormone (LH). HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Format:: Purified
Host:: Mouse
Immunogen:: Recombinant hCG beta protein
Isotype:: Mouse IgG1; kappa
Purification:: Affinity Chromatography
Reactivities:: Human
Shipping Conditions:: Blue Ice
Storage Conditions:: Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:: Abeomics
Type:: Antibodies:Monoclonal Antibody

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