Monoclonal Antibody to Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16(Clone : SPM594)
Product Sizes
100 µg
£716.00
36-1002-100UG
About this Product
- SKU:
- 36-1002
- Additional Names:
- CDH16||UNQ695/PRO1340
- translate.label.attr.clone:
- SPM594
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a protein of 130kDa; identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis; tissue morphogenesis; tissue structure maintenance; cell polarization; neoplastic invasiveness and metastasis; and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney; Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells; and not in glomeruli; renal interstitial cells; or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Recombinant human CDH16 protein
- Isotype:
- Mouse IgG1; kappa
- Purification:
- Affinity Chromatography
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
