ACE2 Antibody
Product Sizes
100 µl
£823.00
35-1875-100UL
About this Product
- SKU:
- 35-1875
- Additional Names:
- ACEH antibody; DKFZp434A014 antibody; ACE2 antibody; metalloprotease MPROT15 antibody; angiotensin-converting enzyme homolog antibody; angiotensin I converting enzyme 2 antibody; ACE-related carboxypeptidase antibody; angiotensin-converting enzyme 2 antibody
- Clonality:
- Polyclonal
- Extra Details:
- Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular; renal; and myocardial physiology. In contrast to its homolog ACE; ACE2 expression is restricted to heart; kidney; and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7; unlike ACE; which converts AngI to AngII. While the role of these vasoactive peptides is not well understood; lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility; indicating its importance in regulating heart function.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- This Antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ACE2.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity chromatography purified via peptide column.
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Stored at -20[o]C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:1.jpg
