Polyclonal Antibody to EPHB2
Product Sizes
50 µl
£511.00
35-1864-50UL
100 µl
£581.00
35-1864-100UL
About this Product
- SKU:
- 35-1864
- Additional Names:
- CAPB|| DRT|| EK5|| EPH receptor B2|| Ephrin type-B receptor 2
- Clonality:
- Polyclonal
- Extra Details:
- Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells; leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons; that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. Beside axon guidance; also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Kalo MS; Yu HH; Pasquale EB. J Biol Chem 276; 38940-8 (2001)
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.896~900 (L-S-S-G-I) derived Human from EPHB2.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
