Polyclonal Antibody to MMP-13
Product Sizes
50 µl
£511.00
35-1863-50UL
100 µl
£581.00
35-1863-100UL
About this Product
- SKU:
- 35-1863
- Additional Names:
- CLG3|| Collagenase 3|| MANDP1|| matrix metallopeptidase 13|| MMP13
- Clonality:
- Polyclonal
- Extra Details:
- Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen; fibronectin; TNC and ACAN. Cleaves triple helical collagens; including type I; type II and type III collagen; but has the highest activity with soluble type II collagen. Can also degrade collagen type IV; type XIV and type X. May also function by activating or degrading key regulatory proteins; such as TGFB1 and CTGF. Plays a role in wound healing; tissue remodeling; cartilage degradation; bone development; bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing; probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.355~359 (F-W-A-L-N) derived Human from MMP-13.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
