Polyclonal Antibody to SCF
Product Sizes
50 µl
£511.00
35-1838-50UL
100 µl
£581.00
35-1838-100UL
About this Product
- SKU:
- 35-1838
- Additional Names:
- SF|| MGF|| FPH2|| KL-1|| Kitl
- Clonality:
- Polyclonal
- Extra Details:
- Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation; hematopoiesis; stem cell maintenance; gametogenesis; mast cell development; migration and function; and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1; the regulatory subunit of phosphatidylinositol 3-kinase; and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS; RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1; STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1; leading to the production of the cellular signaling molecules diacylglycerol and inositol-1;4;5-trisphosphate. KITLG/SCF acts synergistically with other cytokines; probably interleukins.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.265~269(E-K-E-R-E) derived from Human SCF.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
