Polyclonal Antibody to MBP (myelin basic protein)
Product Sizes
50 µl
£511.00
35-1808-50UL
100 µl
£581.00
35-1808-100UL
About this Product
- SKU:
- 35-1808
- Additional Names:
- MGC99675
- Clonality:
- Polyclonal
- Extra Details:
- The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination; maybe as components of transcriptional complexes; and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers; with each of them potentially having a specialized function. Induces T-cell proliferation.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.291~295(G-G-R-D-S
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
