Polyclonal Antibody to hnRNP A1 (Ab-192)
Product Sizes
50 µl
£511.00
35-1754-50UL
100 µl
£581.00
35-1754-100UL
About this Product
- SKU:
- 35-1754
- Additional Names:
- HNRPA1|| HNRPA1L3|| hnRNP A1|| hnRNP-A1|| MGC102835
- Clonality:
- Polyclonal
- Extra Details:
- Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing; metabolism and transport of nuclear pre-mRNA transcripts . hnRNP A1 regulates the alternative splicing of c-Src; c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers; knockdown of hnRNP A1 leads to apoptosis in various cancer cells . Although predominantly nuclear; hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus . hnRNP A1 binds to cis-acting repressive sequences (CRS) of HIV-1 to influence HIV-1 production . HIV-1 enhances hnRNP A1 expression and promotes the relocalization of hnRNP A1 to the cytoplasm ;
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.190~194(S-S-S-Q-R)derived from Human hnRNP A1.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
