Polyclonal Antibody to CD22
Product Sizes
50 µl
£511.00
35-1716-50UL
100 µl
£581.00
35-1716-100UL
About this Product
- SKU:
- 35-1716
- Additional Names:
- SIGLEC2|| FLJ22814|| SIGLEC-2|| MGC130020
- Clonality:
- Polyclonal
- Extra Details:
- Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to a-2;6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.839~843 (N-V-D-Y-V) derived from Human CD22.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
