Polyclonal Antibody to AML1(RUNX1)
Product Sizes
50 µl
£594.00
35-1706-50UL
100 µl
£724.00
35-1706-100UL
About this Product
- SKU:
- 35-1706
- Additional Names:
- CBFA2|| EVI-1|| AMLCR1
- Clonality:
- Polyclonal
- Extra Details:
- CBF binds to the core site; 5'-PYGPYGGT-3'; of a number of enhancers and promoters; including murine leukemia virus; polyomavirus enhancer; T-cell receptor enhancers; LCK; IL-3 and GM-CSF promoters. The a subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.6~10(D-A-S-T-S) derived from Human AML1(RUNX1).
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
