Polyclonal Antibody to REST
Product Sizes
50 µl
£511.00
35-1704-50UL
100 µl
£581.00
35-1704-100UL
About this Product
- SKU:
- 35-1704
- Additional Names:
- NRSF|| XBR|| REST
- Clonality:
- Polyclonal
- Extra Details:
- Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors; mSin3 and CoREST; which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones; thereby acting as a chromatin modifier.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.873~877(R-E-E-A-S) derived from Human REST.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
