Polyclonal Antibody to PKM1/2
Product Sizes
50 µl
£511.00
35-1695-50UL
100 µl
£581.00
35-1695-100UL
About this Product
- SKU:
- 35-1695
- Additional Names:
- PKM|| PK3|| OIP3|| PK2
- Clonality:
- Polyclonal
- Extra Details:
- Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP; generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa. 36~40(D-S-P-P-I) derived from Human PKM1/2.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
