Polyclonal Antibody to Nanog
Product Sizes
50 µl
£511.00
35-1677-50UL
100 µl
£581.00
35-1677-100UL
About this Product
- SKU:
- 35-1677
- Additional Names:
- Homeobox transcription factor Nanog
- Clonality:
- Polyclonal
- Extra Details:
- Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' By similarity. When overexpressed; promotes cells to enter into S phase and proliferation
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.137~141 (K-Q-V-K-T) derived from Nano g
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
