Polyclonal Antibody to Caspase 3
Product Sizes
50 µl
£511.00
35-1674-50UL
100 µl
£581.00
35-1674-100UL
About this Product
- SKU:
- 35-1674
- Additional Names:
- Apopain
- Clonality:
- Polyclonal
- Extra Details:
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6; -7 and -9. Involved in the cleavage of huntingtin. Gervais; F. G et al.Cell 97: 395-406; 1999. Nicholson; D. W. et al. (1995) Nature 376; 37-43.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.29~33 (S-G-I-S-L) derived from Caspase 3.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
