Polyclonal Antibody to Fas
Product Sizes
50 µl
£511.00
35-1673-50UL
100 µl
£581.00
35-1673-100UL
About this Product
- SKU:
- 35-1673
- Additional Names:
- FASLG receptor|| Apoptosis-mediating surface antigen FAS|| Apo-1 antigen
- Clonality:
- Polyclonal
- Extra Details:
- Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance; in the antigen-stimulated suicide of mature T-cells; or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.323~327 (E-N-S-N-F) derived from human Fas .
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
