Polyclonal Antibody to NF-KB-p100/p52 (Ab-872)
Product Sizes
50 µl
£511.00
35-1625-50UL
100 µl
£581.00
35-1625-100UL
About this Product
- SKU:
- 35-1625
- Additional Names:
- DNA-binding factor KBF2|| H2TF1|| Lymphocyte translocation chromosome 10|| Lyt10|| NF-KB2
- Clonality:
- Polyclonal
- Extra Details:
- NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation; immunity; differentiation; cell growth; tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65; RELB; NF-KB1/p105; NF-KB1/p50; REL and NF-KB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors; respectively. Shin HM; et al. (2006) EMBO J; 25(1): 129-138. Li Q; et al. (2005) Proc Natl Acad Sci USA; 102(35): 12425-12430. Chen C; et al. (2000) Mol Cell Biol; 20(8): 2687-2695.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.870~874 (S-Q-S-V-E) derived from Human NF-KB-p100.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
