Polyclonal Antibody to Integrin beta3 (Ab-785)
Product Sizes
50 µl
£511.00
35-1605-50UL
100 µl
£581.00
35-1605-100UL
About this Product
- SKU:
- 35-1605
- Additional Names:
- CD61 antigen|| GP3A|| GPIIIa|| ITB3|| Platelet membrane glycoprotein IIIa
- Clonality:
- Polyclonal
- Extra Details:
- The Itg-Beta3 gene encodes the beta subunit of the platelet membrane adhesive protein receptor complex Itg-Beta3 protein; which belongs to the Integrin class of cell adhesion molecule receptors that share a common heterotrimeric structure with a and Beta subunits. It is a common Beta subunit of the platelet complex and of two other Integrins (Fibronectin and Vitronectin Receptors); which have distinct a subunits. Itg-Beta3 has been implicated in a wide variety of functions; including platelet aggregation and thrombosis and implantation; placentation; angiogenesis; bone remodeling; and tumor progression. Glanzmann Thrombasthenia can result from defects in the genes for either the Itg-a2B or the Itg-Beta3 subunit Sujoy Bhattacharya; et al. (2006) Biochem J. August 1; 397(Pt 3): 437
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.783~787 (I-T-Y-R-G) derived from Human Integrin B3/ITGB3.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
