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Antibodies

Polyclonal Antibody to Merlin (Ab-518)

Product Sizes
50 µl
£511.00
35-1591-50UL
100 µl
£581.00
35-1591-100UL
About this Product
SKU:
35-1591
Additional Names:
MERL|| NF2|| Neurofibromin 2|| SCH|| Schwannomerlin
Clonality:
Polyclonal
Extra Details:
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway; a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around aa.516~520 (R-L-S-M-E) derived from Human Merlin.
Isotype:
Rabbit IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Merlin(Ab-518) Antibody 35-1591 (left) or the same antibody preincubated with blocking peptide(right).
Figure 2: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Merlin(Ab-518) Antibody 35-1591 (left) or the same antibody preincubated with blocking peptide(right).