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Antibodies

Polyclonal Antibody to 4E-BP1 (Ab-36)

Product Sizes
50 µl
£511.00
35-1553-50UL
100 µl
£581.00
35-1553-100UL
About this Product
SKU:
35-1553
Additional Names:
EIF4EBP1|| PHAS-1
Clonality:
Polyclonal
Extra Details:
4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E); which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling; resulting in its dissociation from eIF4E and activation of mRNA translation.
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around aa.34~38 (S-T-T-P-G) derived from Human 4E-BP1.
Isotype:
Rabbit IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 4E-BP1(Ab-36) Antibody 35-1553 (left) or the same antibody preincubated with blocking peptide(right).
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 4E-BP1(Ab-36) Antibody 35-1553 (left) or the same antibody preincubated with blocking peptide(right).