Polyclonal Antibody to SMC1 (Ab-957)
Product Sizes
50 µl
£511.00
35-1529-50UL
100 µl
£581.00
35-1529-100UL
About this Product
- SKU:
- 35-1529
- Additional Names:
- SM1A|| SMC1A|| SMC1L1|| SMC1 alpha protein
- Clonality:
- Polyclonal
- Extra Details:
- Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase; the complex is cleaved and dissociates from chromatin; allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM; or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa. 955~959 (G-S-S-Q-G) derived from Human SMC1.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
