Polyclonal Antibody to Alpha-Synuclein (Ab-129)
Product Sizes
50 µl
£511.00
35-1523-50UL
100 µl
£581.00
35-1523-100UL
About this Product
- SKU:
- 35-1523
- Additional Names:
- NACP|| SYN|| SYUA|| alpha-synuclein
- Clonality:
- Polyclonal
- Extra Details:
- SncA is a member of the synuclein family of structurally related proteins that are prominently expressed in the central nervous system; which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and SncA and Snc-Beta inhibit phospholipase D2 selectively. SncA may serve to integrate presynaptic signaling and membrane trafficking. Aggregated SncA proteins form brain lesions that are hallmarks of neurodegenerative synucleinopathies. Defects in SncA play a role in the pathogenesis of Parkinson disease. SncA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer disease. SncA shares 95% sequence homology with rat SncA. Rat SncA is specifically expressed in brain and is associated with synaptosomal membranes in neurons
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.127~131 (M-P-S-E-E) derived from Human a-Synuclein.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
