Polyclonal Antibody to FKHR (Ab-256)
Product Sizes
50 µl
£511.00
35-1486-50UL
100 µl
£581.00
35-1486-100UL
About this Product
- SKU:
- 35-1486
- Additional Names:
- FOXO1
- Clonality:
- Polyclonal
- Extra Details:
- FKHR belongs to the forkhead family of transcription factors; which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors; FKHR; FKHRL1; and AFX; function as key regulators of insulin signaling; cell cycle progression; and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14 Gan L; et al. (2005) J Neurochem; 93(5): 1209-19. Smith WW; et al. (2005) J Cell Biol; 169(2): 331-9. Di Maira G; et al. (2005) Cell Death Differ; 12(6): 668-77. Horn S; et al. (2004) Leukemia; 18(11): 1839-49. Zhao X; et al. (2004) Biochem J 4; 378(Pt 3): 839-49.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.254~258 (A-A-S-M-D) derived from Human FKHR/FOXO1A.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
