Polyclonal Antibody to TYK2 (Ab-1054)
Product Sizes
50 µl
£511.00
35-1468-50UL
100 µl
£581.00
35-1468-100UL
About this Product
- SKU:
- 35-1468
- Additional Names:
- tyrosine kinase 2|| JTK1
- Clonality:
- Polyclonal
- Extra Details:
- TYK2 encodes a member of the tyrosine kinase and; more specifically; the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such; it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. Zheng H; et al. (2005) Mol Cell Proteomics. 4(6):721-730. Gauzzi MC; et al. (1996) J Biol Chem. 271(34): 20494-20500.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.1052~1056 (H-E-Y-Y-R) derived from Human TYK2.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
