Polyclonal Antibody to MKK3 (Ab-189)
Product Sizes
50 µl
£511.00
35-1466-50UL
100 µl
£581.00
35-1466-100UL
About this Product
- SKU:
- 35-1466
- Additional Names:
- MAP kinase kinase 3|| MAP2K3|| MAPK/ERK kinase 3|| MAPKK 3|| MEK3
- Clonality:
- Polyclonal
- Extra Details:
- MEK3 belongs to MAPKK family. This kinase is activated by mitogenic and environmental stress; and participates in the MAPK-mediated signaling cascade. It phosphorylates and thus activates p38. This kinase can be activated by insulin; and is necessary for the expression of glucose transporter. Expression of Ras oncogene is found to result in the accumulation of the active form of this kinase; which thus leads to the constitutive activation of p38; and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Wang W; et al. (2002) Mol Cell Biol ; 22(10): 3389-403. Raingeaud J; et al. (1996) Mol Cell Biol; 16(3): 1247-55.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around aa.187~191 (V-D-S-V-A) derived from Human MKK3.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
