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Antibodies

Polyclonal Antibody to BAD (Ab-155)

Product Sizes
50 µl
£511.00
35-1418-50UL
100 µl
£581.00
35-1418-100UL
About this Product
SKU:
35-1418
Additional Names:
Bbc2
Clonality:
Polyclonal
Extra Details:
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2; and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase; as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around aa.153~157 (R-M-S-D-E) derived from Mouse BAD.
Isotype:
Rabbit IgG
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BAD(Ab-155) Antibody 35-1418 (left) or the same antibody preincubated with blocking peptide(right).
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BAD(Ab-155) Antibody 35-1418 (left) or the same antibody preincubated with blocking peptide(right).