Polyclonal Antibody to FAK (phospho-Tyr576/Tyr577)
Product Sizes
50 µl
£511.00
35-1327-50UL
100 µl
£581.00
35-1327-100UL
About this Product
- SKU:
- 35-1327
- Additional Names:
- FADK 1|| FAK1|| PTK2
- Clonality:
- Polyclonal
- Extra Details:
- Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility; proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking; or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid; or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. Parsons; J.T. et al. (2000) Oncogene 19; 5606-5613 Schaller; M.D. et al. (1994) Mol. Cell. Biol. 14; 1680-1688. Cobb; B.S. et al. (1994) Mol. Cell. Biol. 14; 147-155. Chen; H.C. et al. (1996) J. Biol. Chem. 271; 26329-26334.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 576/tyrosine 577 (S-T-Y(p)-Y(p)-K-A) derived from Human FAK.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
