Polyclonal Antibody to ABL1/2 (phospho-Tyr393/439)
Product Sizes
50 µl
£511.00
35-1316-50UL
100 µl
£581.00
35-1316-100UL
About this Product
- SKU:
- 35-1316
- Additional Names:
- Abelson murine leukemia viral oncogene homolog 1|| c-ABL|| p150
- Clonality:
- Polyclonal
- Extra Details:
- Regulates cytoskeleton remodeling during cell differentiation; cell division and cell adhesion. Localizes to dynamic actin structures; and phosphorylates CRK and CRKL; DOK1; and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. Wang; J.Y. et al. (2000) Oncogene 19; 5643-5650. Danial; N.N. et al. (2000) Oncogene 19; 2523-2531. Brasher; B.B. et al. (2000) J. Biol. Chem. 275; 35631-35637. Pluk; H. et al. (2002) Cell 108; 247-259.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 393/439 (D-T-Y(p)-T-A) derived from Human ABL1/2.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
