Polyclonal Antibody to Keratin 8 (Phospho-Ser74)
Product Sizes
50 µl
£511.00
35-1277-50UL
100 µl
£581.00
35-1277-100UL
About this Product
- SKU:
- 35-1277
- Additional Names:
- CK 8|| CK8|| CYK8|| Cytokeratin endo A|| K8
- Clonality:
- Polyclonal
- Extra Details:
- Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Nakamichi I; et al. (2002) Mol Biol Cell; 13(10): 3441-3451. Prochasson P; et al. (2002) Nucleic Acids Res; 30(15): 3312-3322. Pankov R; et al. (1994) Proc Natl Acad Sci U S A; 91(3): 873-877. Thorey IS; et al. (1993) Mol Cell Biol; 13(11): 6742-6751
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8).
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
