Polyclonal Antibody to IkB-beta (Phospho-Ser23)
Product Sizes
50 µl
£511.00
35-1274-50UL
100 µl
£581.00
35-1274-100UL
About this Product
- SKU:
- 35-1274
- Additional Names:
- I-kappa-B-beta; IKB-B; IKBB; NF-kappa-BIB; NF-kappaB inhibitor beta
- Clonality:
- Polyclonal
- Extra Details:
- Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However; the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation; explaining its slower degradation. Shirane; M. et al. (1999) J Biol Chem 274; 28169-28174. DiDonato J; et al. (1996) Mol Cell Biol 16(4): 1295-304
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of serine 23 (L-G-S(p)-L-G) derived from Human IkB-b.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
