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Antibodies

Polyclonal Antibody to PKR (Phospho-Thr446)

Product Sizes
50 µl
£511.00
35-1256-50UL
100 µl
£581.00
35-1256-100UL
About this Product
SKU:
35-1256
Additional Names:
ADRB2|| E2AK2|| EIF2AK2|| EIF2aK|| PRKR
Clonality:
Polyclonal
Extra Details:
Following activation by double-stranded RNA in the presence of ATP; the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1; which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection. Abujiang Pataer; et;al. (2002) Cancer Res; 62: 2239. K. D. Ryman; et;al. (2005) J. Virol; 79: 1487 - 1499. Susana Guerra; et;al. (2006) J. Biol. Chem; 281: 18734 - 18745.
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of threonine 446 (K-R-T(p)-R-S) derived from Human PKR.
Isotype:
Rabbit IgG
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg