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Antibodies

Polyclonal Antibody to p56Dok-2 (Phospho-Tyr299)

Product Sizes
50 µl
£511.00
35-1254-50UL
100 µl
£581.00
35-1254-100UL
About this Product
SKU:
35-1254
Additional Names:
DOK2
Clonality:
Polyclonal
Extra Details:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4; as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation Feng Cong; et;al. (1999) Mol. Cell. Biol ; 19: 8314 - 8325. Serge Lemay; et;al. (2000) Mol. Cell. Biol ; 20: 2743 - 2754. Ute Schaeper; et;al.(2000) J. Cell Biol ; 149: 1419. Miyuki Honma; et;al. (2006) Genes Cells; 11: 143 - 151.
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.
Isotype:
Rabbit IgG
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p56Dok-2(Phospho-Tyr299) Antibody 35-1254 (left) or the same antibody preincubated with blocking peptide(right).
Figure 3: Immunofluorescence staining of methanol-fixed Hela cells using p56Dok-2(Phospho-Tyr299) Antibody 35-1254 .
Figure 4: Western blot analysis of extracts from JK cells; treated with G-CSF or calf intestinal phosphatase (CIP); using p56Dok-2 (Phospho-Tyr299) Antibody 35-1254 .
Figure 4: Western blot analysis of extracts from JK cells; treated with G-CSF or calf intestinal phosphatase (CIP); using p56Dok-2 (Phospho-Tyr299) Antibody 35-1254 .