Polyclonal Antibody to Merlin (Phospho-Ser518)
Product Sizes
50 µl
£511.00
35-1245-50UL
100 µl
£581.00
35-1245-100UL
About this Product
- SKU:
- 35-1245
- Additional Names:
- MERL|| NF2|| Neurofibromin 2|| SCH|| Schwannomerlin
- Clonality:
- Polyclonal
- Extra Details:
- Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway; a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Guang-Hui Xiao; et al. (2005) Mol. Cell. Biol ; 25: 2384 - 2394. Hi-Su Yang; et al. (2006) Cancer Res ; 66: 2708 - 2715. R Bohni; et al. (1994) J. Biol. Chem ; 269: 14541 - 14545. Adam J. Ratner; et al. (2001) J. Biol. Chem ; 276: 19267 - 19275.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of serine 518 (R-L-S(p)-M-E) derived from Human Merlin.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
