Polyclonal Antibody to P38 MAPK (Phospho-Tyr182)
Product Sizes
50 µl
£511.00
35-1234-50UL
100 µl
£581.00
35-1234-100UL
About this Product
- SKU:
- 35-1234
- Additional Names:
- MAPK2|| MAPKAPK-2|| MAPKAPK2
- Clonality:
- Polyclonal
- Extra Details:
- Responds to activation by environmental stress; pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors; such as ELK1 and ATF2 and several downstream kinases; such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines; for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis. Ming Zheng; et al.(2005) The FASEB Journal. 19: 109-111 Bernt van den et al.(2001) Blink Immunology; 166: 582-587 Arshad Rahman; et al. (2004) Am J Physiol Lung Cell Mol Physiol 287: L1017-L1024 Osamu Yoshino; et al. (2003) Endocrinology & Metabolism Vol. 88: 2236-2241
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 182 (T-G-Y(p)-V-A) derived from Human P38 MAPK.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
