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Antibodies

Polyclonal Antibody to SAPK/JNK (Phospho-Thr183)

Product Sizes
50 µl
£511.00
35-1231-50UL
100 µl
£581.00
35-1231-100UL
About this Product
SKU:
35-1231
Additional Names:
JNK2
Clonality:
Polyclonal
Extra Details:
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors; primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells; JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Ferrer; et al. (2003) Neuropathology & Applied Neurobiology 29: 23 Zhonghong Guan; et al. (1999) J Biol Chem; Vol. 274: 36200-36206 D.Margriet Ouwens1; et al. (2002)The EMBO Journal 21: 3782
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of threonine 183 (M-M-T(p)-P-Y) derived from Human SAPK/JNK.
Isotype:
Rabbit IgG
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SAPK/JNK(Phospho-Thr183) Antibody 35-1231 (left) or the same antibody preincubated with blocking peptide(right).
Figure 3: Western blot analysis of extracts from 293 cells; treated with UV or calf intestinal phosphatase (CIP); using SAPK/JNK (Phospho-Thr183) Antibody 35-1231 .
Figure 3: Western blot analysis of extracts from 293 cells; treated with UV or calf intestinal phosphatase (CIP); using SAPK/JNK (Phospho-Thr183) Antibody 35-1231 .