Polyclonal Antibody to 4E-BP1 (Phospho-Thr45)
Product Sizes
50 µl
£511.00
35-1209-50UL
100 µl
£581.00
35-1209-100UL
About this Product
- SKU:
- 35-1209
- Additional Names:
- EIF4EBP1|| PHAS-1
- Clonality:
- Polyclonal
- Extra Details:
- 4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E); which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling; resulting in its dissociation from eIF4E and activation of mRNA translation. Gingras AC; et al. (1998) Genes Dev 12(4): 502-513. Brugarolas J; et al. (2004) Genes Dev 18(23): 2893-2904. Kumar V; et al. (2000) EMBO J 19(5): 1087-1097. Moody CA; et al. (2005) J Virol 79(9): 5499-5506. Burnett PE; et al. (1998) Proc Natl Acad Sci U S A 95(4): 1432-1437.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 45 (S-T-T(p)-P-G) derived from Human 4E-BP1.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
