Polyclonal Antibody to FAK (Phospho-Tyr397)
Product Sizes
50 µl
£511.00
35-1201-50UL
100 µl
£581.00
35-1201-100UL
About this Product
- SKU:
- 35-1201
- Additional Names:
- FAK|| FAK1|| PTK2
- Clonality:
- Polyclonal
- Extra Details:
- Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility; proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking; or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid; or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 397(D-D-Y(p)-A-E)derived from Human FAK.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
