Polyclonal Antibody to APP (Phospho-668)
Product Sizes
50 µl
£511.00
35-1180-50UL
100 µl
£581.00
35-1180-100UL
About this Product
- SKU:
- 35-1180
- Additional Names:
- AAA|| AD1|| PN2|| ABPP|| APPI
- Clonality:
- Polyclonal
- Extra Details:
- APP encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation; while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. Hung; A.Y. and Selkoe; D.J. (1994) EMBO J. 13; 534-542. Suzuki; T. et al. (1994) EMBO J. 13; 1114-1122 Ando; K. et al. (1999) J. Neurosci. 19; 4421-4427. Iijima; K.I. et al. (2000) J. Neurochem. 75; 1085-1091
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 668 (A-V-T(p)-P-E) derived from Human APP.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
