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Antibodies

AMPK Alpha1 (Phospho-Ser487) Polyclonal Antibody

Product Sizes
50 µl
£511.00
35-1165-50UL
100 µl
£581.00
35-1165-100UL
About this Product
SKU:
35-1165
Additional Names:
AAPK1|| AMPK alpha-1 chain|| AMPK-alpha1|| HMG-CoA redustase kinase|| PRKAA1
Clonality:
Polyclonal
Extra Details:
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. Kim JE; et al. (2005) J Proteome Res. 4(4): 1339-1346. Woods A; et al. (2003) J Biol Chem. 278(31): 28434-28442.
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of serine 496 (S-G- S(P)-V-S) derived from Human AMPK?1.
Isotype:
Rabbit IgG
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunofluorescence staining of methanol-fixed Hela cells using AMPKa1(Phospho-Ser496)Antibody 35-1165 .
Figure 3: Western blot analysis of extracts from HUVEC cells untreated or treated with UV using AMPKa1 (Phospho-Ser496)Antibody 35-1165 .
Figure 4: Western blot analysis of extracts from C6 cells; treated with EGF or calf intestinal phosphatase (CIP); using AMPKa1 (Phospho-Ser496) Antibody 35-1165 .
Figure 4: Western blot analysis of extracts from C6 cells; treated with EGF or calf intestinal phosphatase (CIP); using AMPKa1 (Phospho-Ser496) Antibody 35-1165 .