Polyclonal Antibody to FKHRL1(Phospho-Ser253)
Product Sizes
50 µl
£511.00
35-1150-50UL
100 µl
£581.00
35-1150-100UL
About this Product
- SKU:
- 35-1150
- Additional Names:
- FOXO2|| AF6q21|| FKHRL1|| FOXO3A|| FKHRL1P2
- Clonality:
- Polyclonal
- Extra Details:
- Transcriptional activator which triggers apoptosis in the absence of survival factors; including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5; promotes induction of miR-34b and miR-34c expression; 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. Lehtinen M.K.; Yuan Z.; Boag P.R.; Yang Y.; Villen J.; Becker E.B.E.; DiBacco S.; de la Iglesia N.; Gygi S.P.; Blackwell T.K.; Bonni A.Cell 125:987-1001(2006) Morishita D.; Katayama R.; Sekimizu K.; Tsuruo T.; Fujita N.Cancer Res. 68:5076-5085(2008)
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of serine 253(A-V-S(p)-M-D) derived from Human FKHRL1.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
