Polyclonal Antibody to p53 (Phospho-Ser15)
Product Sizes
50 µl
£511.00
35-1091-50UL
100 µl
£581.00
35-1091-100UL
About this Product
- SKU:
- 35-1091
- Additional Names:
- Tumor suppressor p53|| Phosphoprotein p53|| Antigen NY-CO-13|| TP53
- Clonality:
- Polyclonal
- Extra Details:
- Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression; or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Lin T; et al. (2005) Nat Cell Biol; 7(2): 165-71. Vega FM; et al. (2004) Mol Cell Biol; 24(23): 10366-80. Li J; et al. (2004) J Biol Chem; 279(40): 41275-9. Wang J; et al. (2004) J Biol Chem; 279(38): 39584-92.
- Format:
- Purified
- Host:
- Rabbit
- Immunogen:
- Peptide sequence around phosphorylation site of serine 15 (P-L-S(p)-Q-E) derived from Human p53.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Polyclonal Antibody
- Manufacturer's Data Sheet:1.jpg
