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Antibodies

Polyclonal Antibody to p53 (Phospho-Ser6)

Product Sizes
50 µl
£511.00
35-1090-50UL
100 µl
£581.00
35-1090-100UL
About this Product
SKU:
35-1090
Additional Names:
Antigen NY-CO-13|| Phosphoprotein p53|| TP53|| Tumor suppressor p53
Clonality:
Polyclonal
Extra Details:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression; or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
Format:
Purified
Host:
Rabbit
Immunogen:
Peptide sequence around phosphorylation site of serine 6 (P-Q-S(p)-D-P) derived from Human p53.
Isotype:
Rabbit IgG
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store the antibody at 4[o]C; stable for 6 months. For long-term storage; store at -20[o]C. Avoid repeated freeze and thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Polyclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p53(Phospho-Ser6) Antibody 35-1090 (left) or the same antibody preincubated with blocking peptide(right).
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p53(Phospho-Ser6) Antibody 35-1090 (left) or the same antibody preincubated with blocking peptide(right).