Recombinant Human NGAL/Lipocalin-2/LCN2 (C-6His; Human Cells)
Product Sizes
10 µg
£549.00
32-9740-10UG
50 µg
£706.00
32-9740-50UG
About this Product
- SKU:
- 32-9740
- Additional Names:
- Neutrophil gelatinase-associated lipocalin; NGAL; 25 kDa alpha-2-microglobulin-relatedsubunit of MMP-9; Lipocalin-2; Oncogene 24p3; Siderocalin LCN2;p25;HNL;NGAL
- Extra Details:
- Source : Human Cells;LCN2 is iron-trafficking protein involved in multiple processes such as apoptosis; innate immunity and renal development. LCN2 binds iron through association with 2;5-dihydroxybenzoic acid (2;5-DHBA); a siderophore that shares structural similarities with bacterial enterobactin; and delivers or removes iron from the cell; depending on the context. LCN2 is involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis; while iron-free form decreases intracellular iron levels; inducing expression of the proapoptotic protein BCL2L11/BIM; resulting in apoptosis. LCN2 is involved in innate immunity; possibly by sequestrating iron; leading to limit bacterial growth.
- Shipping Conditions:
- Dry Ice
- Supplier:
- Abeomics
- Type:
- Cells
- Manufacturer's Data Sheet:download_pdf.php
