Recombinant Mouse GITR/TNFRSF18/CD357 (C-Fc-6His)
Product Sizes
50 µg
£656.00
32-9722-50UG
500 µg
£1464.00
32-9722-500UG
About this Product
- SKU:
- 32-9722
- Additional Names:
- Tumor necrosis factor receptor superfamily member 18;Glucocorticoid-induced TNFR-related protein;Tnfrsf18; AITR;CD357;GITR-D;TNFRSF18
- Extra Details:
- Source : Human Cells;Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA; isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1; TRAF2; and TRAF3; but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
