Recombinant Mouse VEGF-A/VEGF164
Product Sizes
50 µg
£847.00
32-9719-50UG
500 µg
£1959.00
32-9719-500UG
About this Product
- SKU:
- 32-9719
- Additional Names:
- Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGFA; VEGFA164; VEGF164
- Extra Details:
- Source : E. coli;Mouse Vascular endothelial growth factor (VEGF or VEGF-A); is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the PDGF/VEGF growth factor family that is characterized by a cystine knot structure formed by eight conserved cysteine residues. Alternately spliced isoforms of 120; 164 and 188 aa found in mouse. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt-1) and VEGF R2 (Flk-/KDR) on endothelial cells.Although affinity is highest for binding to VEGF R1; VEGF R2 appears to be the primary mediator of VEGF angiogenic activity. VEGF is required during embryogenesis to regulate the proliferation; migration; and survival of endothelial cells.It may play a role in increasing vascular permeability during lactation; when increased transport of molecules from the blood is required for efficient milk protein synthesis.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
