Recombinant Human Activin Receptor 2B/Activin RIIB/ACVR2B (C-Fc-6His)
Product Sizes
50 µg
£554.00
32-9704-50UG
500 µg
£1534.00
32-9704-500UG
About this Product
- SKU:
- 32-9704
- Additional Names:
- Activin Receptor Type-2B; Activin Receptor Type IIB; ACTR-IIB; ACVR2B
- Extra Details:
- Source : Human Cells;Activin proteins that belong to the transforming growth factor-beta (TGF-Beta) superfamily; exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding; type I and II receptors form a stable complex; resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity; and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB; also known as ActRIIB; is a type II receptor containing an extracellular domain (ECD); a transmembrane segment; and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A; activin B and inhibin A. Multiple ActRIIB isoforms can also be generated; which bind activin isoforms with different affinities.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
