Recombinant Human B- and T-Lymphocyte Attenuator/BTLA/CD272 (C-Fc)
Product Sizes
50 µg
£847.00
32-9656-50UG
500 µg
£2101.00
32-9656-500UG
About this Product
- SKU:
- 32-9656
- Additional Names:
- B- and T-Lymphocyte Attenuator; B- and T-Lymphocyte-Associated Protein; CD272; BTLA
- Extra Details:
- Source : Human Cells;B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells; and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4; BTLA interacts with a B7 homolog; B7H4. However; unlike PD-1 and CTLA-4; BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R); not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily; member 14 (TNFRSF14); also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
