Recombinant Human Interleukin-10/IL-10
Product Sizes
50 µg
£847.00
32-9654-50UG
500 µg
£2101.00
32-9654-500UG
About this Product
- SKU:
- 32-9654
- Additional Names:
- Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF; IL10; RP11-262N9.1; IL10A; MGC126450; MGC126451; TGIF
- Extra Details:
- Source : Human Cells;Interleukin 10(IL10); also known as cytokine synthesis inhibitory factor (CSIF);is a secreted protein and belongs to the IL-10 family. IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells; keratinocytes; and placental cytotrophoblasts . IL-10 is an anti-inflammatory TH2 cytokine that has a critical role in limiting the immune response to pathogens to prevent host damage. As IL-10 in produced in several T helper populations; it is proposed that it provides a feedback loop to limit the effector functions of macrophages and DCs on T cells. Once expressed; IL-10 signals through the IL-10 receptor (IL-10R) to activate STAT3. As IL-10 is a strong inhibitor of inflammation; it has become a viable biomarker for various diseases and conditions as well as a therapeutic molecule for certain conditions. In addition to elevated levels in parasitic infection; high expression levels of IL-10 are also found in retroviral infections inducing immunodeficiency. The immunosuppressive properties of IL-10 suggest a possible clinical use of IL-10 in suppressing rejections of grafts after organ transplantations
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
