Recombinant Cynomolgus ICOS/AILIM/CD278 (C-Fc)
Product Sizes
50 µg
£656.00
32-9636-50UG
500 µg
£1959.00
32-9636-500UG
About this Product
- SKU:
- 32-9636
- Additional Names:
- Inducible T-cell costimulator;activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1;ICOS
- Extra Details:
- Source : Human Cells;Inducible T-cell costimulator; also known as activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1 and ICOS; belongs to the CD28 and CTLA4 cell surface receptor family. ICOS contains one Ig-like V-type domain and exsits as a homodimer with disulfide-linked. ICOS is highly expressed on tonsillar T-cellsand can be induced by PMA and ionomycin; ICOS plays an important role in cell-cell signaling; immune responses; and regulation of cell proliferation. Defects in ICOS are the cause of immunodeficiency common variable type 1; which is a primary immunodeficiency characterized by antibody deficiency; hypogammaglobulinemia; recurrent bacterial infections and an inability to mount an antibody response to antigen.
- Shipping Conditions:
- Ambient
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:download_pdf.php
